Before beginning any road trip check your RV out, even if you just went camping last weekend.
A problem you may not have noticed last week, like a oil leak, a cracked hose, low tire pressure or loose or broken fasteners on your awning or doors may have gotten bad enough to show up now that the vehicle has sat for a week. Check your fluid levels, tire pressure and tug on any restraining straps, bike racks, ladders etc. to ensure they're still snug and secure.